Physalin H, physalin B, and isophysalin B suppress the quorum-sensing function of Staphylococcus aureus by binding to AgrA

• Päätekijät: Junpei Yamaguchi (Tekijä), Teruhisa Manome (Tekijä), Yasumasa Hara (Tekijä), Yuriko Yamazaki (Tekijä), Yuumi Nakamura (Tekijä), Masami Ishibashi (Tekijä), Akiko Takaya (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

The virulence of Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), depends on the expression of toxins and virulence factors controlled by the quorum-sensing (QS) system, encoded on the virulence accessory gene regulator (agr) locus. The aim of this study was to identify a phy...