Physalin H, physalin B, and isophysalin B suppress the quorum-sensing function of Staphylococcus aureus by binding to AgrA

• मुख्य लेखकों: Junpei Yamaguchi (लेखक), Teruhisa Manome (लेखक), Yasumasa Hara (लेखक), Yuriko Yamazaki (लेखक), Yuumi Nakamura (लेखक), Masami Ishibashi (लेखक), Akiko Takaya (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The virulence of Staphylococcus aureus, including methicillin-resistant S. aureus (MRSA), depends on the expression of toxins and virulence factors controlled by the quorum-sensing (QS) system, encoded on the virulence accessory gene regulator (agr) locus. The aim of this study was to identify a phy...