Regulation of mitochondrial oxidative stress by β-arrestins in cultured human cardiac fibroblasts
Oxidative stress in cardiac fibroblasts (CFs) promotes transformation to myofibroblasts and collagen synthesis leading to myocardial fibrosis, a precursor to heart failure (HF). NADPH oxidase 4 (Nox4) is a major source of cardiac reactive oxygen species (ROS); however, mechanisms of Nox4 regulation...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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The Company of Biologists,
2015-12-01T00:00:00Z.
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