The Protective Effects of Shengmai Formula Against Myocardial Injury Induced by Ultrafine Particulate Matter Exposure and Myocardial Ischemia are Mediated by the PI3K/AKT/p38 MAPK/Nrf2 Pathway

• Main Authors: Lina Chen (Author), Yuan Guo (Author), Shuiqing Qu (Author), Kai Li (Author), Ting Yang (Author), Yuanmin Yang (Author), Zhongyuan Zheng (Author), Hui Liu (Author), Xi Wang (Author), Shuoqiu Deng (Author), Yu Zhang (Author), Xiaoxin Zhu (Author), Yujie Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and Purpose: Ultrafine particulate matter (UFPM) induces oxidative stress (OS) and is considered to be a risk factor of myocardial ischemia (MI). Shengmai formula (SMF) is a traditional Chinese medicine with antioxidant properties and has been used to treat cardiovascular diseases for a l...