In vivo protective effects of chlorogenic acid against triptolide-induced hepatotoxicity and its mechanism

• Main Authors: Jun-Ming Wang (Author), Rong-Xing Chen (Author), Lu-Lu Zhang (Author), Ning-Ning Ding (Author), Chen Liu (Author), Ying Cui (Author), Yong-Xian Cheng (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context: Triptolide (TP) has outstanding biological activities, but it induces toxicities, particular hepatotoxicity, severely limiting its clinical application. Chlorogenic acid (CGA) has prominently medicinal and nutritional values. However, until now, it is not known whether CGA could mitigate TP...