Development and optimization of proniosomal gel containing etodolac: in-vitro, ex-vivo and in-vivo evaluation

• Главные авторы: Moreshwar Patil (Автор), Prashant Pandit (Автор), Pavan Udavant (Автор), Sandeep Sonawane (Автор), Deepak Bhambere (Автор)
• Формат: ‌
• Опубликовано: Facultad de Farmacia, Universidad de Granada, 2021-09-01T00:00:00Z.
• Предметы: article
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Abstract Introduction: Etodolac is used in the treatment of acute pain and inflammation. It has low solubility because of high hydrophobicity and it is reported that upon oral administration shows gastric disturbances. This encourages the development of topical vesicular formulation. Method: In this...