Development and optimization of proniosomal gel containing etodolac: in-vitro, ex-vivo and in-vivo evaluation

• Main Authors: Moreshwar Patil (Author), Prashant Pandit (Author), Pavan Udavant (Author), Sandeep Sonawane (Author), Deepak Bhambere (Author)
• Format: Book
• Published: Facultad de Farmacia, Universidad de Granada, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction: Etodolac is used in the treatment of acute pain and inflammation. It has low solubility because of high hydrophobicity and it is reported that upon oral administration shows gastric disturbances. This encourages the development of topical vesicular formulation. Method: In this...