Effects of 071031B, a novel serotonin and norepinephrine reuptake inhibitor, on monoamine system in mice and rats

• Main Authors: Rui Xue (Author), Xin-Hua He (Author), Li Yuan (Author), Hong-Xia Chen (Author), Li-Ming Zhang (Author), Zheng Yong (Author), Gang Yu (Author), Shi-Yong Fan (Author), Yun-Feng Li (Author), Bo-Hua Zhong (Author), You-Zhi Zhang (Author)
• Format: Book
• Published: Elsevier, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Our previous study indicated that 071031B, a novel potential serotonin and norepinephrine reuptake inhibitor, showed robust antidepressant activity in multiple depression models, and could simultaneously inhibit 5-HT and NE reuptake in vitro. The present study was to evaluate the effects of 071031B...