Notch Signaling Pathway Was Involved in Regulating Programmed Cell Death 1 Expression during Sepsis-Induced Immunosuppression

• Egile Nagusiak: Tingting Pan (Egilea), Zhaojun Liu (Egilea), Jianyong Yin (Egilea), Tianyun Zhou (Egilea), Jialin Liu (Egilea), Hongping Qu (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2015-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Programmed cell death 1 (PD-1) plays an important pathologic role in sepsis-induced immunosuppression. However, whether PD-1 overexpression occurs early during septic shock is unknown and its regulation mechanism is also unknown. Our study investigated the expressions of PD-1/programmed death-ligand...