Notch Signaling Pathway Was Involved in Regulating Programmed Cell Death 1 Expression during Sepsis-Induced Immunosuppression

• Główni autorzy: Tingting Pan (Autor), Zhaojun Liu (Autor), Jianyong Yin (Autor), Tianyun Zhou (Autor), Jialin Liu (Autor), Hongping Qu (Autor)
• Format: Książka
• Wydane: Hindawi Limited, 2015-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Programmed cell death 1 (PD-1) plays an important pathologic role in sepsis-induced immunosuppression. However, whether PD-1 overexpression occurs early during septic shock is unknown and its regulation mechanism is also unknown. Our study investigated the expressions of PD-1/programmed death-ligand...