A subset of microRNAs in the Dlk1‐Dio3 cluster regulates age‐associated muscle atrophy by targeting Atrogin‐1

• Main Authors: Yeo Jin Shin (Author), Eun‐Soo Kwon (Author), Seung‐Min Lee (Author), Seon‐Kyu Kim (Author), Kyung‐Won Min (Author), Jae‐Young Lim (Author), Bora Lee (Author), Jae Sook Kang (Author), Ju Yeon Kwak (Author), Young Hoon Son (Author), Jeong Yi Choi (Author), Yong Ryul Yang (Author), Seokho Kim (Author), Yeon‐Soo Kim (Author), Hak C. Jang (Author), Yousin Suh (Author), Je‐Hyun Yoon (Author), Kwang‐Pyo Lee (Author), Ki‐Sun Kwon (Author)
• Format: Book
• Published: Wiley, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The microRNAs (miRNAs) down‐regulated in aged mouse skeletal muscle were mainly clustered within the delta‐like homologue 1 and the type III iodothyronine deiodinase (Dlk1‐Dio3) genomic region. Although clustered miRNAs are coexpressed and regulate multiple targets in a specific...