Purification Process of a Recombinant Human Follicle Stimulating Hormone Biosimilar (Primapur^®) to Yield a Pharmaceutical Product with High Batch-to-Batch Consistency

• Glavni autori: Maria Sinegubova (Autor), Ivan Vorobiev (Autor), Anatoly Klishin (Autor), Dmitry Eremin (Autor), Nadezhda Orlova (Autor), Natalya Orlova (Autor), Mikhail Polzikov (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2022-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Recombinant human follicle stimulating hormone (r-hFSH) is widely used for infertility treatment and is subject to the development of biosimilars. There are different purification strategies that can yield r-hFSH of pharmaceutical quality from Chinese hamster ovary cell culture broth. We developed a...