Repurposing econazole as a pharmacological autophagy inhibitor to treat pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is characterized by the highest mortality among carcinomas. The pathogenesis of PDAC requires elevated autophagy, inhibition of which using hydroxychloroquine has shown promise. However, current realization is impeded by its suboptimal use and unpredictable to...
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Elsevier,
2022-07-01T00:00:00Z.
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