Curcumin activates the p38MPAK-HSP25 pathway <it>in vitro </it>but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLC

• Main Authors: Natarajan Rama (Author), LaPage Janine (Author), Dai Tiane (Author), Wang Ying (Author), Phillips Lynetta (Author), Ma Jun (Author), Adler Sharon G (Author)
• Format: Book
• Published: BMC, 2010-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Curcumin has anti-inflammatory, anti-oxidant, and anti-proliferative properties, and depending upon the experimental circumstances, may be pro- or anti-apoptotic. Many of these biological actions could ameliorate diabetic nephropathy...