In Vitro and In Vivo Evaluation of Lactoferrin-Modified Liposomal Etomidate with Enhanced Brain-Targeting Effect for General Anesthesia

• Main Authors: Ailing Wu (Author), Houyin Shi (Author), Luhan Yang (Author), Hao Zhang (Author), Xichen Nan (Author), Dan Zhang (Author), Zhuo Zhang (Author), Chun Zhang (Author), Siwei Chen (Author), Xiujuan Fu (Author), Lilan Ou (Author), Lulu Wang (Author), Yanyan Shi (Author), Hao Liu (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Etomidate is a general anesthetic that has shown good hemodynamic stability without significant cardiovascular or respiratory depression. Despite several kinds of dosage forms having been reported for this drug, formulation types are very limited in clinical practice, and brain-targeted formulations...