Circulating fibrocytes traffic to the lung in murine acute lung injury and predict outcomes in human acute respiratory distress syndrome: a pilot study

• Main Authors: Christine M. Lin (Author), Abdullah Alrbiaan (Author), John Odackal (Author), Zhimin Zhang (Author), Yogesh Scindia (Author), Sun-Sang J. Sung (Author), Marie D. Burdick (Author), Borna Mehrad (Author)
• Format: Book
• Published: BMC, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Fibrosis is an integral component of the pathogenesis of acute lung injury and is associated with poor outcomes in patients with acute respiratory distress syndrome (ARDS). Fibrocytes are bone marrow-derived cells that traffic to injured tissues and contribute to fibrosis; hence...