Interleukin 12 receptor deficiency in a child with recurrent bronchopneumonia and very high IgE levels

• Main Authors: Palamaro Loredana (Author), Giardino Giuliana (Author), Santamaria Francesca (Author), Romano Rosa (Author), Fusco Anna (Author), Montella Silvia (Author), Salerno Mariacarolina (Author), Ursini Matilde (Author), Pignata Claudio (Author)
• Format: Book
• Published: BMC, 2012-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Interleukin-12 (IL-12) is involved in cellular immune responses against intracellular pathogens by promoting the generation of T naive in T helper 1 (Th1) cells and by increasing interferon-gamma (IFN-gamma) production from T and natural killer (NK) cells. A defe...