Clinical assessment of momelotinib drug-drug interactions via CYP3A metabolism and transporters

Abstract Momelotinib-approved for treatment of myelofibrosis in adults with anemia-and its major active metabolite, M21, were assessed as drug-drug interaction (DDI) victims with a strong cytochrome P450 (CYP) 3A4 inhibitor (multiple‐dose ritonavir), an organic anion transporting polypeptide (OATP)...

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Main Authors: Yu Liu Ho (Author), Pete Gorycki (Author), Geraldine Ferron‐Brady (Author), Paul Martin (Author), Georgios Vlasakakis (Author)
Format: Book
Published: Wiley, 2024-04-01T00:00:00Z.
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