A Robust Bioassay of the Human Bradykinin B₂ Receptor That Extends Molecular and Cellular Studies: The Isolated Umbilical Vein

• Main Authors: François Marceau (Author), Hélène Bachelard (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2021-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Bradykinin (BK) has various physiological and pathological roles. Medicinal chemistry efforts targeted toward the widely expressed BK B₂ receptor (B₂R), a G-protein-coupled receptor, were primarily aimed at developing antagonists. The only B<sub>2&...