Peripheral Neuroprotective and Immunomodulatory Effects of 5α-Reductase Inhibitors in Parkinson's Disease Models

• Main Authors: Andrée-Anne Poirier (Author), Mélissa Côté (Author), Hend Jarras (Author), Nadhir Litim (Author), Jérôme Lamontagne-Proulx (Author), Sara Al-Sweidi (Author), Marc Morissette (Author), Asmaa Lachhab (Author), Martin Pelletier (Author), Thérèse Di Paolo (Author), Denis Soulet (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gastrointestinal disorders in Parkinson's disease (PD) have been associated with neuronal alteration in the plexus of the gut. We previously demonstrated the immunomodulatory effect of female hormones to treat enteric neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)...