Study the Antifungal and Ocular Permeation of Ketoconazole from Ophthalmic Formulations Containing Trans-Ethosomes Nanoparticles

• Glavni autori: Tarek A. Ahmed (Autor), Maram M. Alzahrani (Autor), Alaa Sirwi (Autor), Nabil A. Alhakamy (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2021-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Ketoconazole (KET), a synthetic imidazole broad-spectrum antifungal agent, is characterized by its poor aqueous solubility and high molecular weight, which might hamper its corneal permeation. The aim was to develop an ophthalmic formulation loaded with optimized trans-ethosomal vesicles to enhance...