α2-macroglobulin-rich serum as a master inhibitor of inflammatory factors attenuates cartilage degeneration in a mini pig model of osteoarthritis induced by "idealized" anterior cruciate ligament reconstruction

• Main Authors: Ruipeng Zhao (Author), Xiaochun Wei (Author), Chengming Zhang (Author), Hongru Wu (Author), Chuan Xiang (Author), Haoqian Li (Author), Wangping Duan (Author), Zhiqing Duan (Author), Chunjiang Li (Author), Yu Zhao (Author), Lingan Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Post-traumatic osteoarthritis is a special type of osteoarthritis and a common disease, with few effective treatments available. α2-Macroglobulin (α2M) is important to chondral protection in post-traumatic osteoarthritis. However, its injection into xenogeneic joint cavities involves safety hazards,...