Concurrent hypermethylation of DNMT1, MGMT and EGFR genes in progression of gliomas

• Autori principali: Gömöri Éva (Autore), Pál József (Autore), Kovács Bernadett (Autore), Dóczi Tamás (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2012-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Gliomas are the most common neoplasm of the brain. High-grade gliomas often resist treatment even with aggressive surgical resection and adjuvant radiation and chemotherapy. Despite the combined treatment, they frequently recur with...