Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome

• Main Authors: Clark R. Sims (Author), Sharda P. Singh (Author), Shengyu Mu (Author), Neriman Gokden (Author), Dala Zakaria (Author), Trung C. Nguyen (Author), Philip R. Mayeux (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

While the mortality rate associated with sepsis in children has fallen over the years, it still remains unacceptably high. The development of both acute cardiac dysfunction and acute kidney injury during severe sepsis is categorized as type 5 cardiorenal syndrome (CRS) and is poorly understood in in...