Hybrids of Imatinib with Quinoline: Synthesis, Antimyeloproliferative Activity Evaluation, and Molecular Docking

Imatinib (IMT) is the first-in-class BCR-ABL commercial tyrosine kinase inhibitor (TKI). However, the resistance and toxicity associated with the use of IMT highlight the importance of the search for new TKIs. In this context, heterocyclic systems, such as quinoline, which is present as a pharmacoph...

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Main Authors: Carine Santos (Author), Luiz Pimentel (Author), Henayle Canzian (Author), Andressa Oliveira (Author), Floriano Junior (Author), Rafael Dantas (Author), Lucas Hoelz (Author), Debora Marinho (Author), Anna Cunha (Author), Monica Bastos (Author), Nubia Boechat (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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