A proof-of-concept study to investigate the radiolabelling of human mesenchymal and hematopoietic stem cells with [89Zr]Zr-Df-Bz-NCS

• Main Authors: Maryke Kahts (Author), Juanita Mellet (Author), Chrisna Durandt (Author), Kinosha Moodley (Author), Beverley Summers (Author), Thomas Ebenhan (Author), Jan Rijn Zeevaart (Author), Omer Aras (Author), Michael S. Pepper (Author)
• Format: Book
• Published: SpringerOpen, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The transplantation of hematopoietic stem and progenitor cells (HSPCs) or mesenchymal stromal/stem cells (MSCs) for the treatment of a wide variety of diseases has been studied extensively. A challenge with cell-based therapies is that migration to and retention at the target sit...