Identification of the Key Role of NF-κB Signaling Pathway in the Treatment of Osteoarthritis With Bushen Zhuangjin Decoction, a Verification Based on Network Pharmacology Approach

• Hauptverfasser: Yunteng Xu (Verfasst von), Hui Li (Verfasst von), Xiaojuan He (Verfasst von), Yanfeng Huang (Verfasst von), Shengjie Wang (Verfasst von), Lili Wang (Verfasst von), Changlong Fu (Verfasst von), Hongzhi Ye (Verfasst von), Xihai Li (Verfasst von), Tetsuya Asakawa (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

This study aimed to identify whether the NF-κB signaling pathway plays a key role in the treatment of osteoarthritis (OA) with Bushen Zhuangjin Decoction (BZD) based on a typical network pharmacology approach (NPA). Four sequential experiments were performed: 1) conventional high-performance liquid...