Identification of the Key Role of NF-κB Signaling Pathway in the Treatment of Osteoarthritis With Bushen Zhuangjin Decoction, a Verification Based on Network Pharmacology Approach

• Main Authors: Yunteng Xu (Author), Hui Li (Author), Xiaojuan He (Author), Yanfeng Huang (Author), Shengjie Wang (Author), Lili Wang (Author), Changlong Fu (Author), Hongzhi Ye (Author), Xihai Li (Author), Tetsuya Asakawa (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study aimed to identify whether the NF-κB signaling pathway plays a key role in the treatment of osteoarthritis (OA) with Bushen Zhuangjin Decoction (BZD) based on a typical network pharmacology approach (NPA). Four sequential experiments were performed: 1) conventional high-performance liquid...