Sulodexide Prevents Hyperglycemia-Induced Endothelial Dysfunction and Oxidative Stress in Porcine Retinal Arterioles

• Main Authors: Alice Dauth (Author), Andrzej Bręborowicz (Author), Yue Ruan (Author), Qi Tang (Author), Jenia K. Zadeh (Author), Elsa W. Böhm (Author), Norbert Pfeiffer (Author), Pratik H. Khedkar (Author), Andreas Patzak (Author), Ksenija Vujacic-Mirski (Author), Andreas Daiber (Author), Adrian Gericke (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetes mellitus may cause severe damage to retinal blood vessels. The central aim of this study was to test the hypothesis that sulodexide, a mixture of glycosaminoglycans, has a protective effect against hyperglycemia-induced endothelial dysfunction in the retina. Functional studies were performe...