Reversible Tau Phosphorylation Induced by Synthetic Torpor in the Spinal Cord of the Rat

• Main Authors: Timna Hitrec (Author), Fabio Squarcio (Author), Matteo Cerri (Author), Davide Martelli (Author), Alessandra Occhinegro (Author), Emiliana Piscitiello (Author), Domenico Tupone (Author), Roberto Amici (Author), Marco Luppi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tau is a key protein in neurons, where it affects the dynamics of the microtubule system. The hyperphosphorylation of Tau (PP-Tau) commonly leads to the formation of neurofibrillary tangles, as it occurs in tauopathies, a group of neurodegenerative diseases, including Alzheimer's. Hypothermia-r...