Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells

• Үндсэн зохиолчид: Romeo Romagnoli (Зохиогч), Filippo Prencipe (Зохиогч), Luisa Carlota Lopez-Cara (Зохиогч), Paola Oliva (Зохиогч), Stefania Baraldi (Зохиогч), Pier Giovanni Baraldi (Зохиогч), Francisco Estévez-Sarmiento (Зохиогч), José Quintana (Зохиогч), Francisco Estévez (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

The combination of two pharmacophores into a single molecule represents one of the methods that can be adopted for the synthesis of new anticancer molecules. To investigate the influence of the position of the pyridine nitrogen on biological activity, two different series of α-bromoacryloylamido ind...