Chemotherapeutic potential of 17-AAG against cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis.

• Main Authors: Diego M Santos (Author), Antonio L O A Petersen (Author), Fabiana S Celes (Author), Valeria M Borges (Author), Patricia S T Veras (Author), Camila I de Oliveira (Author)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

BACKGROUND: Leishmaniasis remains a worldwide public health problem. The limited therapeutic options, drug toxicity and reports of resistance, reinforce the need for the development of new treatment options. Previously, we showed that 17-(allylamino)-17-demethoxygeldanamycin (17-AAG), a Heat Shock P...