The Influence of Milling on the Dissolution Performance of Simvastatin

Particle size reduction is a simple means to enhance the dissolution rate of poorly water soluble BCS-class II and IV drugs. However, the major drawback of this process is the possible introduction of process induced disorder. Drugs with different molecular arrangements may exhibit altered propertie...

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Bibliographic Details
Main Authors: Thomas Rades (Author), Clare J. Strachan (Author), Ulrike Zimper (Author), Jaakko Aaltonen (Author), Keith C. Gordon (Author), Karen Krauel-Goellner (Author)
Format: Book
Published: MDPI AG, 2010-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available