Development of a competitive enzyme-linked immunosorbent assay for therapeutic drug monitoring of afatinib

• Main Authors: Rintaro Sogawa (Author), Tetsuya Saita (Author), Yuta Yamamoto (Author), Sakiko Kimura (Author), Yutaka Narisawa (Author), Shinya Kimura (Author), Masashi Shin (Author)
• Format: Book
• Published: Elsevier, 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Afatinib is an oral tyrosine kinase inhibitor (TKI) approved for treating advanced non-small cell lung cancer. It is necessary to develop a simple quantification method for TKIs in order to facilitate therapeutic drug monitoring (TDM) in clinical settings. This study sought to develop a simple and s...