Development of a competitive enzyme-linked immunosorbent assay for therapeutic drug monitoring of afatinib

• Autors principals: Rintaro Sogawa (Autor), Tetsuya Saita (Autor), Yuta Yamamoto (Autor), Sakiko Kimura (Autor), Yutaka Narisawa (Autor), Shinya Kimura (Autor), Masashi Shin (Autor)
• Format: Llibre
• Publicat: Elsevier, 2019-02-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Afatinib is an oral tyrosine kinase inhibitor (TKI) approved for treating advanced non-small cell lung cancer. It is necessary to develop a simple quantification method for TKIs in order to facilitate therapeutic drug monitoring (TDM) in clinical settings. This study sought to develop a simple and s...