WNT7A Promotes EGF-Induced Migration of Oral Squamous Cell Carcinoma Cells by Activating β-Catenin/MMP9-Mediated Signaling

• Main Authors: Hui Xie (Author), Yadong Ma (Author), Jun Li (Author), Huixia Chen (Author), Yongfu Xie (Author), Minzhen Chen (Author), Xuyang Zhao (Author), Sijie Tang (Author), Shuo Zhao (Author), Yujie Zhang (Author), Jun Du (Author), Feimin Zhang (Author), Luo Gu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims and hypothesisEpidermal growth factor (EGF) has been shown to induce the migration of various cancer cells. However, the underlying signaling mechanisms for EGF-induced migration of oral squamous cell carcinoma (OSCC) remain to be elucidated. WNT7A, a member of the family of 19 Wnt secreted gly...