Integration of ATAC-seq and RNA-seq identifies human alpha cell and beta cell signature genes

Objective: Although glucagon-secreting α-cells and insulin-secreting β-cells have opposing functions in regulating plasma glucose levels, the two cell types share a common developmental origin and exhibit overlapping transcriptomes and epigenomes. Notably, destruction of β-cells can stimulate repopu...

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Main Authors: Amanda M. Ackermann (Author), Zhiping Wang (Author), Jonathan Schug (Author), Ali Naji (Author), Klaus H. Kaestner (Author)
Format: Book
Published: Elsevier, 2016-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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