P-Selectin Targeted Dexamethasone-Loaded Lipid Nanoemulsions: A Novel Therapy to Reduce Vascular Inflammation

• Asıl Yazarlar: Viorel Simion (Yazar), Cristina Ana Constantinescu (Yazar), Daniela Stan (Yazar), Mariana Deleanu (Yazar), Monica Madalina Tucureanu (Yazar), Elena Butoi (Yazar), Ileana Manduteanu (Yazar), Maya Simionescu (Yazar), Manuela Calin (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Hindawi Limited, 2016-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Inflammation is a common process associated with numerous vascular pathologies. We hypothesized that targeting the inflamed endothelium by coupling a peptide with high affinity for P-selectin to the surface of dexamethasone-loaded lipid nanoemulsions will highly increase their specific binding to ac...