Superoxide Dismutase-1 Intracellular Content in T Lymphocytes Associates with Increased Regulatory T Cell Level in Multiple Sclerosis Subjects Undergoing Immune-Modulating Treatment

• Main Authors: Valentina Rubino (Author), Anna Teresa Palatucci (Author), Giuliana La Rosa (Author), Angela Giovazzino (Author), Francesco Aruta (Author), Simona Damiano (Author), Flavia Carriero (Author), Mariarosaria Santillo (Author), Rosa Iodice (Author), Paolo Mondola (Author), Giuseppina Ruggiero (Author), Giuseppe Terrazzano (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reactive oxygen species (ROS) participate in the T-cell activation processes. ROS-dependent regulatory networks are usually mediated by peroxides, which are more stable and able to freely migrate inside cells. Superoxide dismutase (SOD)-1 represents the major physiological intracellular source of pe...