Dissecting Efficacy and Metabolic Characteristic Mechanism of Taxifolin on Renal Fibrosis by Multivariate Approach and Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometry-Based Metabolomics Strategy

Taxifolin (TFN) is an important natural compound with antifibrotic activity; however, its pharmacological mechanism is not clear. In this study, our aim is to gain insight into the effects of TFN and its potential mechanisms in unilateral ureteral obstruction (UUO) animal model using metabolomics ap...

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Main Authors: Lei Ren (Author), Hao-Nan Guo (Author), Jun Yang (Author), Xiao-Ying Guo (Author), Ye-Sheng Wei (Author), Zhao Yang (Author)
Format: Book
Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
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