Solubilization of Paclitaxel with Natural Compound Rubusoside toward Improving Oral Bioavailability in a Rodent Model

Paclitaxel, which features low water solubility and permeability, is an efflux pump substrate. The current paclitaxel drugs are given intravenously after resolving the solubility issue. Yet, oral delivery to achieve therapeutic bioavailability is not effective due to low absorption. This study evalu...

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Main Authors: Jian Zhang (Author), Jicheng Shu (Author), Rhett W. Stout (Author), Paul S. Russo (Author), Zhijun Liu (Author)
Format: Book
Published: MDPI AG, 2024-08-01T00:00:00Z.
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3rd Floor Main Library

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