Synthesis, Activity, Toxicity, and In Silico Studies of New Antimycobacterial <i>N</i>-Alkyl Nitrobenzamides

• Main Authors: João P. Pais (Author), Olha Antoniuk (Author), David Pires (Author), Tiago Delgado (Author), Andreia Fortuna (Author), Paulo J. Costa (Author), Elsa Anes (Author), Luis Constantino (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tuberculosis (TB) is a disease that plagues the frailest members of society. We have developed a family of <i>N</i>-alkyl nitrobenzamides that exhibit promising antitubercular activities and can be considered a structural simplification of known inhibitors of decaprenylphosphoryl-β-D-rib...