Pravastatin induces NO synthesis by enhancing microsomal arginine uptake in healthy and preeclamptic placentas

• Main Authors: Zita Pánczél (Author), Zoltán Kukor (Author), Dorina Supák (Author), Bence Kovács (Author), András Kecskeméti (Author), Rita Czizel (Author), Magdolna Djurecz (Author), Bálint Alasztics (Author), Krisztián Benedek Csomó (Author), András Hrabák (Author), Sándor Valent (Author)
• Format: Book
• Published: BMC, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Pravastatin, a known inducer of endothelial nitric-oxide synthase (eNOS) was demonstrated in human placenta, however the exact mechanism of it's action is not fully understood. Since placental NO (nitric oxide) synthesis is of primary importance in the regulation of placenta...