ApoA-I Nanoparticles as Curcumin Carriers for Cerebral Endothelial Cells: Improved Cytoprotective Effects against Methylglyoxal

• Main Authors: Sai Sandhya Narra (Author), Sarah Rosanaly (Author), Philippe Rondeau (Author), Jessica Patche (Author), Bryan Veeren (Author), Marie-Paule Gonthier (Author), Wildriss Viranaicken (Author), Nicolas Diotel (Author), Palaniyandi Ravanan (Author), Christian Lefebvre d' Hellencourt (Author), Olivier Meilhac (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Methylglyoxal (MGO) is a highly reactive metabolite of glucose present at elevated levels in diabetic patients. Its cytotoxicity is associated with endothelial dysfunction, which plays a role in cardiovascular and cerebrovascular complications. Although curcumin has many therapeutic benefits, these...