Evaluation of a Novel Dry Powder Surfactant Aerosol Delivery System for Use in Premature Infants Supported with Bubble CPAP

• Main Authors: Robert M. DiBlasi (Author), Coral N. Crandall (Author), Rebecca J. Engberg (Author), Kunal Bijlani (Author), Dolena Ledee (Author), Masaki Kajimoto (Author), Frans J. Walther (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aerosolized lung surfactant therapy during nasal continuous positive airway pressure (CPAP) support avoids intubation but is highly complex, with reported poor nebulizer efficiency and low pulmonary deposition. The study objective was to evaluate particle size, operational compatibility, and drug de...