Histone deacetylase 2 (HDAC2) attenuates lipopolysaccharide (LPS)-induced inflammation by regulating PAI-1 expression

• मुख्य लेखकों: Wen-Feng Fang (लेखक), Yu-Mu Chen (लेखक), Chiung-Yu Lin (लेखक), Hui-Lin Huang (लेखक), Hua Yeh (लेखक), Ya-Ting Chang (लेखक), Kuo-Tung Huang (लेखक), Meng-Chih Lin (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2018-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Sepsis is a life-threatening organ dysfunction caused by dysregulated host response to infection, and is primarily characterized by an uncontrolled systemic inflammatory response. In the present study, we developed an effective adjunct therapy mediated by a novel mechanism, to at...