Assessment of Novel Muscarinic Acetylcholine Receptors in Rat Cerebral Cortex by a Tissue Segment Binding Method

• Main Authors: Kung-Shing Lee (Author), Atsushi Nishimune (Author), Hatsumi Yoshiki (Author), Abu Syed Md Anisuzzaman (Author), Fumiko Suzuki (Author), Mao-Hsien Wang (Author), Juei-Tang Cheng (Author), Ikunobu Muramatsu (Author)
• Format: Book
• Published: Elsevier, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Muscarinic acetylcholine receptors (mAChRs) of rat cerebral cortex were evaluated using a tissue segment radioligand binding assay. [3H]-Quinuclidinyl benzilate (QNB, a hydrophobic ligand) specifically bound to mAChRs in the cortex segments. The total mAChRs level was approximately 2,000 fmol/mg pro...