Hyperosmolarity in children with hyperammonemia: a risk of brain herniation at the start of renal replacement therapy

• Main Authors: Yousra Maghmoul (Author), Arnaud Wiedemann (Author), Lucile Barcat (Author), Fabienne Parente (Author), Pierre Allard (Author), Fernando Alvarez (Author), Philippe Jouvet (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

PurposeRenal replacement therapy (RRT) is used in hyperammonemia to reduce the concentration of ammonia in the blood. In the case of plasma hyperosmolarity, RRT can also rapidly decrease plasma osmolarity, which may increase cerebral edema in these patients and favor the occurrence of brain herniati...