Effect of insulin insufficiency on ultrastructure and function in skeletal muscle

• Main Authors: Chantal Kopecky (Author), Michael Haug (Author), Barbara Reischl (Author), Nandan Deshpande (Author), Bikash Manandhar (Author), Thomas W. King (Author), Victoria Lee (Author), Marc R. Wilkins (Author), Margaret Morris (Author), Patsie Polly (Author), Oliver Friedrich (Author), Kerry‐Anne Rye (Author), Blake J. Cochran (Author)
• Format: Book
• Published: Wiley, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Decreased insulin availability and high blood glucose levels, the hallmark features of poorly controlled diabetes, drive disease progression and are associated with decreased skeletal muscle mass. We have shown that mice with β‐cell dysfunction and normal insulin sensitivity have...