Is There a Metabolic Program in the Skeletal Muscle of Obese Individuals?
Severe obesity (BMI ≥ 40 kg/m2) is associated with multiple defects in skeletal muscle which contribute to insulin resistance and a reduction in fatty acid oxidation (FAO) in this tissue. These metabolic derangements are retained in human skeletal muscle cells raised in culture. Together, these find...
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Hindawi Limited,
2011-01-01T00:00:00Z.
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