Development of a depot formulation with an in situ non-lamellar liquid crystal-forming system with phospholipids

• Egile Nagusiak: Hiroaki Todo (Egilea), Rina Niki (Egilea), Akie Okada (Egilea), Ibuki Narita (Egilea), Kazuya Inamura (Egilea), Ayu Ito (Egilea), Shoko Itakura (Egilea), Ichiro Hijikuro (Egilea), Kenji Sugibayashi (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2023-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Non-lamellar liquid crystal (NLLC) structures have gained increasing attention for the controlled release of entrapped drugs. In the present study, an in situ NLLC structure-forming depot formulation through contact with water was developed using a ternary mixture system of soya phosphatidyl choline...