Scoping Review on Use of Drugs Targeting Interleukin 1 Pathway in DIRA and DITRA

• Main Authors: Francisco Gómez-García (Author), Juan L. Sanz-Cabanillas (Author), Isabel Viguera-Guerra (Author), Beatriz Isla-Tejera (Author), Antonio Vélez-García Nieto (Author), Juan Ruano (Author)
• 格式: 图书
• 出版: Adis, Springer Healthcare, 2018-11-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Introduction Deficiencies in interleukin (IL)-1 receptor (IL-R) antagonist (DIRA) and IL-36R antagonist (DITRA) are rare genetic autoinflammatory diseases related to alterations in antagonists of the IL-1 pathway. IL-1 antagonists may represent therapeutic alternatives. Here, we aim to prov...