Curcumin Inhibits the Proteinase-Activated Receptor-2-Triggered Prostaglandin E2 Production by Suppressing Cyclooxygenase-2 Upregulation and Akt-Dependent Activation of Nuclear Factor-κB in Human Lung Epithelial Cells
We performed this study to determine if curcumin affects pro-inflammatory responses to activation of proteinase-activated receptor-2 (PAR2) in human pulmonary adenocarcinoma A549 cells. Curcumin completely inhibited the PAR2-triggered prostaglandin E2 (PGE2) production, but notably not interleukin-8...
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Format: | Book |
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Elsevier,
2010-01-01T00:00:00Z.
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A1234.567 |
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