Curcumin Inhibits the Proteinase-Activated Receptor-2-Triggered Prostaglandin E2 Production by Suppressing Cyclooxygenase-2 Upregulation and Akt-Dependent Activation of Nuclear Factor-κB in Human Lung Epithelial Cells

We performed this study to determine if curcumin affects pro-inflammatory responses to activation of proteinase-activated receptor-2 (PAR2) in human pulmonary adenocarcinoma A549 cells. Curcumin completely inhibited the PAR2-triggered prostaglandin E2 (PGE2) production, but notably not interleukin-8...

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Main Authors: Kazumi Moriyuki (Author), Fumiko Sekiguchi (Author), Kaori Matsubara (Author), Hiroyuki Nishikawa (Author), Atsufumi Kawabata (Author)
Format: Book
Published: Elsevier, 2010-01-01T00:00:00Z.
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3rd Floor Main Library

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