Spatial Learning of Mice Lacking a Neuron-Specific Epidermal Growth Factor Family Protein, NELL2

• Main Authors: Shogo Matsuyama (Author), Nobutaka Doe (Author), Naoki Kurihara (Author), Katsuyuki Tanizawa (Author), Shun'ichi Kuroda (Author), Hiroyuki Iso (Author), Masato Horie (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

NELL2 is a neuron-specific thrombospondin-1-like extracellular protein containing six epidermal growth factor-like domains. We previously disrupted the NELL2 gene in mice by gene targeting and showed that long-term potentiation is enhanced in vivo in the dentate gyrus of NELL2-deficient mice. To fur...