Persistent Inflammation in the CNS during Chronic EAE Despite Local Absence of IL-17 Production

• Main Authors: Sofia Fernanda Gonçalves Zorzella-Pezavento (Author), Fernanda Chiuso-Minicucci (Author), Thais Graziela Donegá França (Author), Larissa Lumi Watanabe Ishikawa (Author), Larissa Camargo da Rosa (Author), Camila Marques (Author), Maura Rosane Valerio Ikoma (Author), Alexandrina Sartori (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Experimental autoimmune encephalomyelitis (EAE) is an artificially induced demyelination of the central nervous system (CNS) that resembles multiple sclerosis in its clinical, histopathological, and immunological features. Activated Th1 and Th17 cells are thought to be the main immunological players...